Publikationen Lehrstuhl 2

Publikationen LS2

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Aberle T., Walter A., Piefke S., Hillgärtner S., Wüst H., Wegner M., Küspert M.:
Sox10 Activity and the Timing of Schwann Cell Differentiation Are Controlled by a Tle4-Dependent Negative Feedback Loop
In: International Journal of Molecular Sciences 25 (2024), Art.Nr.: 5234
ISSN: 1422-0067
DOI: 10.3390/ijms25105234
Jörg L., Schlötzer-Schrehardt U., Lefebvre V., Sock E., Wegner M.:
Transcription Factors Sox8 and Sox10 Contribute with Different Importance to the Maintenance of Mature Oligodendrocytes
In: International Journal of Molecular Sciences 25 (2024), Art.Nr.: 8754
ISSN: 1422-0067
DOI: 10.3390/ijms25168754
Kremp M., Aberle T., Sock E., Bohl B., Hillgärtner S., Winkler J., Wegner M.:
Transcription factor Olig2 is a major downstream effector of histone demethylase Phf8 during oligodendroglial development
In: Glia 72 (2024), S. 1435-1450
ISSN: 0894-1491
DOI: 10.1002/glia.24538
Liu X., Xin DE., Zhong X., Zhao C., Li Z., Zhang L., Dourson AJ., Lee L., Mishra S., Bayat AE., Nicholson E., Seibel WL., Yan B., Mason J., Turner BJ., Gonsalvez DG., Ong W., Chew SY., Ghosh B., Yoon SO., Xin M., He Z., Tchieu J., Wegner M., Nave KA., Franklin RJ., Dutta R., Trapp BD., Hu M., Smith MA., Jankowski MP., Barton SK., He X., Lu QR.:
Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration
In: Cell 187 (2024), S. 2465-2484.e22
ISSN: 0092-8674
DOI: 10.1016/j.cell.2024.04.005
Peters C., Aberle T., Sock E., Brunner J., Küspert M., Hillgärtner S., Wüst H., Wegner M.:
Voltage-Gated Ion Channels Are Transcriptional Targets of Sox10 during Oligodendrocyte Development
In: Cells 13 (2024), Art.Nr.: 1159
ISSN: 2073-4409
DOI: 10.3390/cells13131159
Rupprecht J., Reiprich S., Baroti T., Christoph C., Sock E., Fröb F., Wegner M.:
Transcription Factors Sox2 and Sox3 Directly Regulate the Expression of Genes Involved in the Onset of Oligodendrocyte Differentiation
In: Cells 13 (2024), Art.Nr.: 935
ISSN: 2073-4409
DOI: 10.3390/cells13110935
Schmidt AL., Kremp M., Aratake T., Cui S., Lin Y., Zhong X., Lu QR., Zhang C., Qiu M., Aberle T., Wegner M.:
The myelination-associated G protein-coupled receptor 37 is regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte differentiation
In: Glia (2024)
ISSN: 0894-1491
DOI: 10.1002/glia.24530

Freudenstein D., Lippert M., Popp JS., Aprato J., Wegner M., Sock E., Haase S., Linker RA., González Alvarado MN.:
Endogenous Sox8 is a critical factor for timely remyelination and oligodendroglial cell repletion in the cuprizone model
In: Scientific Reports 13 (2023), Art.Nr.: 22272
ISSN: 2045-2322
DOI: 10.1038/s41598-023-49476-5
Gehlen-Breitbach S., Schmid T., Fröb F., Rodrian G., Weider M., Wegner M., Gölz L.:
The Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development
In: International Journal of Oral Science 15 (2023), S. 16-
ISSN: 1674-2818
DOI: 10.1038/s41368-023-00222-7
Hassel L., Fröb F., Küspert M., Hillgärtner S., Arnold P., Huang W., Kirchhoff F., Wegner M.:
Differential activity of transcription factor Sox9 in early and adult oligodendroglial progenitor cells
In: Glia (2023)
ISSN: 0894-1491
DOI: 10.1002/glia.24373
Kozlenkov A., Vadukapuram R., Zhou P., Fam P., Wegner M., Dracheva S.:
Novel method of isolating nuclei of human oligodendrocyte precursor cells reveals substantial developmental changes in gene expression and H3K27ac histone modification
In: Glia (2023)
ISSN: 0894-1491
DOI: 10.1002/glia.24462
Waldhauser V., Baroti T., Fröb F., Wegner M.:
PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development
In: Cells 12 (2023), Art.Nr.: 1556
ISSN: 2073-4409
DOI: 10.3390/cells12121556

Aberle T., Piefke S., Hillgärtner S., Tamm ER., Wegner M., Küspert M.:
Transcription factor Zfp276 drives oligodendroglial differentiation and myelination by switching off the progenitor cell program
In: Nucleic Acids Research 50 (2022), S. 1951-1968
ISSN: 0305-1048
DOI: 10.1093/nar/gkac042
Bernhardt C., Sock E., Fröb F., Hillgärtner S., Nemer M., Wegner M.:
KLF9 and KLF13 transcription factors boost myelin gene expression in oligodendrocytes as partners of SOX10 and MYRF
In: Nucleic Acids Research (2022)
ISSN: 0305-1048
DOI: 10.1093/nar/gkac953
Fröb F., Wegner M.:
Coordination of Schwann cell myelination and node formation at the transcriptional level
In: Neural Regeneration Research 17 (2022), S. 1269-1270
ISSN: 1673-5374
DOI: 10.4103/1673-5374.327343
Polanetzki V., Fröb F., Baroti T., Schimmel M., Tamm ER., Wegner M.:
Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development
In: Scientific Reports 12 (2022), S. 2651-
ISSN: 2045-2322
DOI: 10.1038/s41598-022-06588-8

Aberle T., Piefke S., Hillgärtner S., Schimmel M., Tamm ER., Wegner M., Küspert M.:
Zinc-finger transcription factor Zfp276 acts as a novel regulator of oligodendroglial differentiation
In: GLIA, HOBOKEN: 2021
Bernhardt C., Sock E., Wegner M.:
Analysis of Kruppel like factors in oligodendroglial differentiation and myelin gene expression
In: GLIA, HOBOKEN: 2021
Engler L., Wegner M.:
Analysis of ectopic Sox9 expression in NG2 glia of the adult murine brain
In: GLIA, HOBOKEN: 2021
Froeb-Thiele F., Tamm ER., Eichele G., Wegner M.:
The Influence of the histone acetylase Tip60 on Schwann Cell Development in mice
In: GLIA, HOBOKEN: 2021
Ittner E., Hartwig A., Elsesser O., Wüst H., Fröb F., Wedel M., Schimmel M., Tamm ER., Wegner M., Sock E.:
SoxD transcription factor deficiency in Schwann cells delays myelination in the developing peripheral nervous system
In: Scientific Reports 11 (2021), Art.Nr.: 14044
ISSN: 2045-2322
DOI: 10.1038/s41598-021-93437-9
Munguba H., Chattopadhyaya B., Nilsson S., Carrico JN., Memic F., Oberst P., Batista-Brito R., Munoz-Manchado AB., Wegner M., Fishell G., Di Cristo G., Hjerling-Leffler J.:
Postnatal Sox6 Regulates Synaptic Function of Cortical Parvalbumin-Expressing Neurons
In: Journal of Neuroscience 41 (2021), S. 8876-8886
ISSN: 0270-6474
DOI: 10.1523/JNEUROSCI.0021-21.2021
Saur AL., Fröb F., Weider M., Wegner M.:
Formation of the node of Ranvier by Schwann cells is under control of transcription factor Sox10
In: Glia (2021)
ISSN: 0894-1491
DOI: 10.1002/glia.23973
Sock E., Wegner M.:
Using the lineage determinants Olig2 and Sox10 to explore transcriptional regulation of oligodendrocyte development
In: Developmental Neurobiology (2021)
ISSN: 1932-8451
DOI: 10.1002/dneu.22849
Vogel J., Wegner M.:
Sox9 in the developing central nervous system: A jack of all trades?
In: Neural Regeneration Research 16 (2021), S. 676-677
ISSN: 1673-5374
DOI: 10.4103/1673-5374.295327
Vogel JK., Wegner M.:
Astroglial changes induced by Gfap-dependent expression of a Sox9 transgene
In: GLIA, HOBOKEN: 2021
Wittmann MT., Katada S., Sock E., Kirchner P., Ekici AB., Wegner M., Nakashima K., Lie DC., Reis A.:
scRNA sequencing uncovers a TCF4-dependent transcription factor network regulating commissure development in mouse
In: Development 148 (2021), Art.Nr.: dev196022
ISSN: 1477-9129
DOI: 10.1242/DEV.196022
Wüst H., Wegener A., Fröb F., Hartwig A., Wegwitz F., Kari VL., Schimmel M., Tamm ER., Johnsen SA., Wegner M., Sock E.:
H2B monoubiquitination is essential for peripheral myelination and guided by Egr2 in Schwann cells
In: GLIA, HOBOKEN: 2021

Aprato J., Sock E., Weider M., Elsesser O., Fröb F., Wegner M.:
Myrf guides target gene selection of transcription factor Sox10 during oligodendroglial development
In: Nucleic Acids Research 48 (2020), S. 1254-1270
ISSN: 0305-1048
DOI: 10.1093/nar/gkz1158
Hauberg ME., Creus-Muncunill J., Bendl J., Kozlenkov A., Zeng B., Corwin C., Chowdhury S., Kranz H., Hurd YL., Wegner M., Børglum AD., Dracheva S., Ehrlich ME., Fullard JF., Roussos P.:
Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons
In: Nature Communications 11 (2020), Art.Nr.: 5581
ISSN: 2041-1723
DOI: 10.1038/s41467-020-19319-2
Kozlenkov A., Vermunt MW., Apontes P., Li J., Hao K., Sherwood CC., Hof PR., Ely JJ., Wegner M., Mukamel EA., Creyghton MP., Koonin EV., Dracheva S.:
Evolution of regulatory signatures in primate cortical neurons at cell-type resolution
In: Proceedings of the National Academy of Sciences of the United States of America 117 (2020), S. 28422-28432
ISSN: 0027-8424
DOI: 10.1073/pnas.2011884117
Mertelmeyer S., Weider M., Baroti T., Reiprich S., Fröb F., Stolt C., Wagner KU., Wegner M.:
The transcription factor Sox10 is an essential determinant of branching morphogenesis and involution in the mouse mammary gland
In: Scientific Reports 10 (2020), Art.Nr.: 17807
ISSN: 2045-2322
DOI: 10.1038/s41598-020-74664-y
Sagar ., Pokrovskii M., Herman JS., Naik S., Sock E., Zeis P., Lausch U., Wegner M., Tanriver Y., Littman DR., Gruen D.:
Deciphering the regulatory landscape of fetal and adult gamma delta T-cell development at single-cell resolution
In: EMBO Journal 39 (2020)
ISSN: 0261-4189
DOI: 10.15252/embj.2019104159
Sagar ., Pokrovskii M., Herman JS., Naik S., Sock E., Zeis P., Lausch U., Wegner M., Tanriver Y., Littman DR., Grün D.:
Deciphering the regulatory landscape of fetal and adult γδ T-cell development at single-cell resolution
In: EMBO Journal (2020)
ISSN: 0261-4189
DOI: 10.15252/embj.2019104159
Wang J., Wang J., Yang L., Zhao C., Wu LN., Xu L., Zhang F., Weng Q., Wegner M., Lu QR.:
CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair
In: Nature Communications 11 (2020), Art.Nr.: 4133
ISSN: 2041-1723
DOI: 10.1038/s41467-020-17955-2
Wedel M., Fröb F., Elsesser O., Wittmann MT., Lie DC., Reis A., Wegner M.:
Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation
In: Nucleic Acids Research 48 (2020), S. 4839-4857
ISSN: 0305-1048
DOI: 10.1093/nar/gkaa218
Weider M., Schröder A., Docheva D., Rodrian G., Enderle I., Seidel CL., Andreev D., Wegner M., Bozec A., Deschner J., Kirschneck C., Proff P., Gölz L.:
A human periodontal ligament fibroblast cell line as a new model to study periodontal stress
In: International Journal of Molecular Sciences 21 (2020), S. 1-10
ISSN: 1422-0067
DOI: 10.3390/ijms21217961
Wittstatt J., Weider M., Wegner M., Reiprich S.:
MicroRNA miR-204 regulates proliferation and differentiation of oligodendroglia in culture
In: Glia (2020)
ISSN: 0894-1491
DOI: 10.1002/glia.23821
Wüst H., Wegener A., Fröb F., Hartwig A., Wegwitz F., Kari V., Schimmel M., Tamm ER., Johnsen SA., Wegner M., Sock E.:
Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination
In: Nucleic Acids Research 48 (2020), S. 8959-8976
ISSN: 0305-1048
DOI: 10.1093/nar/gkaa606

Aprato J., Küspert M., Weider M., Fröb F., Wegner M.:
Myrf as a molecular switch for target gene selection of Sox10 during oligodendroglial development
14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
In: GLIA, HOBOKEN: 2019
Cantone M., Küspert M., Reiprich S., Lai X., Eberhardt M., Göttle P., Beyer F., Azim K., Küry P., Wegner M., Vera J.:
A gene regulatory architecture that controls region-independent dynamics of oligodendrocyte differentiation
In: Glia (2019)
ISSN: 0894-1491
DOI: 10.1002/glia.23569
Elsesser O., Fröb F., Küspert M., Tamm ER., Fujii T., Fukunaga R., Wegner M.:
Chromatin remodeler Ep400 ensures oligodendrocyte survival and is required for myelination in the vertebrate central nervous system
In: Nucleic Acids Research 47 (2019), S. 6208-6224
ISSN: 0305-1048
DOI: 10.1093/nar/gkz376
Elsesser O., Wegner M.:
Influence of chromatin remodeler Ep400 on oligodendroglial development
14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
In: GLIA, HOBOKEN: 2019
Fröb F., Sock E., Tamm ER., Saur AL., Hillgärtner S., Williams TJ., Fujii T., Fukunaga R., Wegner M.:
Ep400 deficiency in Schwann cells causes persistent expression of early developmental regulators and peripheral neuropathy
In: Nature Communications 10 (2019)
ISSN: 2041-1723
DOI: 10.1038/s41467-019-10287-w
Fröb F., Sock E., Wegner M.:
The influence of Ep400 on Schwann cell development in mice
14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
In: GLIA, HOBOKEN: 2019
Fröb F., Wegner M.:
The role of chromatin remodeling complexes in Schwann cell development
In: Glia (2019)
ISSN: 0894-1491
DOI: 10.1002/glia.23766
Küspert M., Reiprich S., Cantone M., Weider M., Baroti T., Wittstatt J., Vera J., Wegner M.:
Transcription factor Sox10 induces the microRNAs miR-335, miR-338 and miR-155 to ensure correct timing of oligodendrocyte development
14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
In: GLIA, HOBOKEN: 2019
Sock E., Wegner M.:
Transcriptional control of myelination and remyelination
In: Glia (2019)
ISSN: 0894-1491
DOI: 10.1002/glia.23636
Vogel J., Weider M., Engler L., Hillgärtner S., Schmitt C., Hermans-Borgmeyer I., Wegner M.:
Sox9 overexpression exerts multiple stage-dependent effects on mouse spinal cord development
In: Glia (2019)
ISSN: 0894-1491
DOI: 10.1002/glia.23752
Vogel J., Weider M., Wegner M.:
Sox9-overexpression promotes gliogenesis at the expense of neurogenesis in the embryonic mouse spinal cord
14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
In: GLIA, HOBOKEN: 2019
Wedel M., Wegner M.:
The role of Tcf4 in oligodendrocyte development
14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
In: GLIA, HOBOKEN: 2019
Wegner M.:
Transcriptional control in myelinating glia: from extrinsic signals to intrinsic factors and networks
ISN-ASN Meeting (Montreal, 4. August 2019 - 8. August 2019)
In: JOURNAL OF NEUROCHEMISTRY, HOBOKEN: 2019
Wittstatt J., Weider M., Reiprich S., Wegner M.:
Impact of the microRNA family miR-204/-211 on the oligodendroglial gene regulatory network
14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
In: GLIA, HOBOKEN: 2019
Wüst H., Wegener A., Johnson S., Fröb F., Wegner M., Sock E.:
Epigenetic regulation in myelinating glia: the role of histone 2b monoubiquitination in Schwann cells
14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
In: GLIA, HOBOKEN: 2019

Hoffmann A., Ettle B., Battis K., Reiprich S., Schlachetzki J., Masliah E., Wegner M., Kuhlmann T., Riemenschneider MJ., Winkler J.:
Oligodendroglial α-synucleinopathy-driven neuroinflammation in multiple system atrophy
In: Brain Pathology (2018)
ISSN: 1015-6305
DOI: 10.1111/bpa.12678
Jacob A., Wüst H., Thalhammer J., Fröb F., Küspert M., Reiprich S., Balta EA., Lie DC., Wegner M., Sock E.:
The transcription factor prospero homeobox protein 1 is a direct target of SoxC proteins during developmental vertebrate neurogenesis
In: Journal of Neurochemistry 146 (2018), S. 251-268
ISSN: 0022-3042
DOI: 10.1111/jnc.14456
Kozlenkov A., Li J., Apontes P., Hurd YL., Byne WM., Koonin E., Wegner M., Mukamel EA., Dracheva S.:
A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons
In: Science Advances 4 (2018)
ISSN: 2375-2548
DOI: 10.1126/sciadv.aau6190
Menzel-Severing J., Zenkel M., Polisetti N., Sock E., Wegner M., Kruse F., Schlötzer-Schrehardt U.:
Transcription factor profiling identifies Sox9 as regulator of proliferation and differentiation in corneal epithelial stem/progenitor cells
In: Scientific Reports 8 (2018)
ISSN: 2045-2322
DOI: 10.1038/s41598-018-28596-3
Neirijnck Y., Reginensi A., Renkema KY., Massa F., Kozlov VM., Dhib H., Bongers EMHF., Feitz WF., Van Eerde AM., Lefebvre V., Knoers NVAM., Tabatabaei M., Schulz H., Mcneill H., Schaefer F., Wegner M., Sock E., Schedl A.:
Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT).
In: Kidney International 93 (2018), S. 1142-1153
ISSN: 0085-2538
DOI: 10.1016/j.kint.2017.11.026
Parfejevs V., Debbache J., Shakhova O., Schaefer SM., Glausch M., Wegner M., Suter U., Riekstina U., Werner S., Sommer L.:
Injury-activated glial cells promote wound healing of the adult skin in mice.
In: Nature Communications 9 (2018), S. 236
ISSN: 2041-1723
DOI: 10.1038/s41467-017-01488-2
Prochnicki A., Amann KU., Wegner M., Sock E., Pfister E., Shankland S., Pippin J., Daniel C.:
Characterization of Glomerular Sox9+ Cells in Anti-Glomerular Basement Membrane Nephritis in the Rat
In: American Journal of Pathology 188 (2018), S. 2529-2541
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2018.07.023
Rich CA., Perera SN., Andratschke J., Stolt C., Buehler DP., Southard-Smith EM., Wegner M., Britsch S., Baker CVH.:
Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting
In: Glia 66 (2018), S. 2617-2631
ISSN: 0894-1491
DOI: 10.1002/glia.23515
Truch K., Arter J., Turnescu T., Weider M., Hartwig A., Tamm ER., Sock E., Wegner M.:
Analysis of the human SOX10 mutation Q377X in mice and its implications for genotype-phenotype correlation in SOX10-related human disease.
In: Human Molecular Genetics 27 (2018), S. 1078-1092
ISSN: 0964-6906
DOI: 10.1093/hmg/ddy029
Turnescu T., Arter J., Reiprich S., Tamm ER., Reiprich S., Waisman A., Wegner M.:
Sox8 and Sox10 jointly maintain myelin gene expression in oligodendrocytes.
In: Glia 66 (2018), S. 279-294
ISSN: 0894-1491
DOI: 10.1002/glia.23242
Weider M., Starost LJ., Groll K., Küspert M., Sock E., Wedel M., Fröb F., Schmitt C., Baroti T., Hartwig A., Hillgärtner S., Piefke S., Fadler T., Ehrlich M., Ehlert C., Stehling M., Albrecht S., Jabali A., Schoeler HR., Winkler J., Kuhlmann T., Wegner M.:
Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning.
In: Nature Communications 9 (2018), S. 899
ISSN: 2041-1723
DOI: 10.1038/s41467-018-03336-3
Weider M., Starost LJ., Groll K., Küspert M., Sock E., Wedel M., Fröb F., Schmitt C., Baroti T., Hartwig A., Hillgärtner S., Piefke S., Fadler T., Ehrlich M., Ehlert C., Stehling M., Albrecht S., Jabali A., Schoeler HR., Winkler J., Kuhlmann T., Wegner M.:
Publisher Correction: Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning
In: Nature Communications 9 (2018)
ISSN: 2041-1723
DOI: 10.1038/s41467-018-03871-z
Wüst H., Wegner M.:
Oncogenic insult to the brain: Sox proteins rise to the occasion.
In: TRANSLATIONAL CANCER RESEARCH 7 (2018), S. S31-S33
ISSN: 2218-676X
DOI: 10.21037/tcr.2017.12.19

Cantone M., Eberhardt M., Küspert M., Reiprich S., Wegner M., Vera J.:
A web tool for the oligodendrocyte differentiation data and network analysis
Duncan GJ., Plemel JR., Assinck P., Manesh SB., Muir FGW., Hirata R., Berson M., Liu J., Wegner M., Emery B., Moore GRW., Tetzlaff W.:
Myelin Regulatory Factor 1 Drives Remyelination in Multiple Sclerosis.
In: Acta Neuropathologica (2017), S. 403-422
ISSN: 0001-6322
DOI: 10.1007/s00401-017-1741-7
Küspert M., Sock E., Wegner M.:
The role of zinc finger transcription factor Zfp276 during glial development
Marathe HG., Watkins-Chow DE., Weider M., Hoffmann A., Trivedi A., Aras S., Mehta G., Basuroy T., Mehrotra A., Bennett DC., Wegner M., Pavan WJ., De La Serna IL.:
BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation.
In: Nucleic Acids Research 45 (2017), S. 6442-6458
ISSN: 0305-1048
DOI: 10.1093/nar/gkx259
Mehta P., Küspert M., Bale T., Brownstein CA., Towne MC., De Girolami U., Shi J., Beggs AH., Darras BT., Wegner M., Piao X., Agrawal PB.:
Novel mutation in CNTNAP1 results in congenital hypomyelinating neuropathy.
In: Muscle & Nerve (2017), S. 761-765
ISSN: 0148-639X
DOI: 10.1002/mus.25416
Reiprich S., Cantone M., Weider M., Baroti T., Wittstatt J., Schmitt C., Küspert M., Vera J., Wegner M.:
Transcription factor Sox10 regulates oligodendroglial Sox9 levels via microRNAs.
In: Glia 65 (2017), S. 1089-1102
ISSN: 0894-1491
DOI: 10.1002/glia.23146
Wegener A., Küspert M., Sock E., Philipsen S., Suske G., Wegner M.:
Sp2 is the only glutamine-rich Specificity protein with minor impact on development and differentiation in myelinating glia.
In: Journal of Neurochemistry 140 (2017), S. 245-256
ISSN: 0022-3042
DOI: 10.1111/jnc.13908
Weider M., Schmitt C., Hillgärtner S., Wegner M.:
Nkx2.2 is a direct target gene of Sox10 in oligodendroglia
Weider M., Wegner M.:
SoxE factors: Transcriptional regulators of neural differentiation and nervous system development.
In: Seminars in Cell & Developmental Biology (2017), S. 35-42.
ISSN: 1084-9521
DOI: 10.1016/j.semcdb.2016.08.013

Baroti T., Schillinger A., Wegner M., Stolt C.:
Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes
In: Journal of Neurochemistry 136 (2016), S. 316-28
ISSN: 0022-3042
DOI: 10.1111/jnc.13414
Baroti T., Zimmermann Y., Schillinger A., Liu L., Lommes P., Wegner M., Stolt C.:
Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain
In: Glia 64 (2016), S. 122-38
ISSN: 0894-1491
DOI: 10.1002/glia.22919
Ettle B., Kerman BE., Valera E., Gillmann C., Schlachetzki J., Reiprich S., Büttner C., Ekici AB., Reis A., Wegner M., Bäuerle T., Riemenschneider MJ., Masliah E., Gage FH., Winkler J.:
?-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy
In: Acta Neuropathologica 132 (2016), S. 59-75
ISSN: 0001-6322
DOI: 10.1007/s00401-016-1572-y
Kozlenkov A., Wang M., Roussos P., Rudchenko S., Barbu M., Bibikova M., Klotzle B., Dwork AJ., Zhang B., Hurd YL., Koonin EV., Wegner M., Dracheva S.:
Substantial DNA methylation differences between two major neuronal subtypes in human brain
In: Nucleic Acids Research 44 (2016), S. 2593-612
ISSN: 0305-1048
DOI: 10.1093/nar/gkv1304
Küspert M., Wegner M.:
SomethiNG 2 talk about-Transcriptional regulation in embryonic and adult oligodendrocyte precursors
In: Brain Research 1638 (2016), S. 167-82
ISSN: 0006-8993
DOI: 10.1016/j.brainres.2015.07.024
Muth K., Piefke S., Weider M., Sock E., Hermans-Borgmeyer I., Wegner M., Küspert M.:
The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes
In: Glia 64 (2016), S. 2120-2132
ISSN: 0894-1491
DOI: 10.1002/glia.23044
Quintes S., Brinkmann BG., Ebert M., Fröb F., Kungl T., Arlt FA., Tarabykin V., Huylebroeck D., Meijer D., Suter U., Wegner M., Sereda MW., Nave KA.:
Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair
In: Nature Neuroscience 19 (2016), S. 1050-9
ISSN: 1097-6256
DOI: 10.1038/nn.4321
Stolt C., Wegner M.:
Schwann cells and their transcriptional network: Evolution of key regulators of peripheral myelination
In: Brain Research 1641 (2016), S. 101-10
ISSN: 0006-8993
DOI: 10.1016/j.brainres.2015.09.025
Moyon S., Huynh J.L, Dutta D., Zhang F., Ma D., Yoo S., Lawrence R., Wegner Michael, John G.R., Emery B., Lubetzki C., Franklin R.J.M., Fan G., Zhu J., Dupree J.L, Casaccia P.:
Functional characterization of DNA methylation in the oligodendrocyte lineage.
In: Cell Reports (2016), S. 748-760
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2016.03.060

Amaya DA., Wegner M., Stolt C., Chehrehasa F., Ekberg JAK., St John JA.:
Radial glia phagocytose axonal debris from degenerating overextending axons in the developing olfactory bulb
In: Journal of Comparative Neurology 523 (2015), S. 183-96
ISSN: 0021-9967
DOI: 10.1002/cne.23665
Anderson SR., Lee I., Ebeling C., Stephenson DA., Schweitzer KM., Baxter D., Moon TM., Lapierre S., Jaques B., Silvius D., Wegner M., Hood LE., Carlson G., Gunn TM.:
Disrupted SOX10 function causes spongiform neurodegeneration in gray tremor mice
In: Mammalian Genome 26 (2015), S. 80-93
ISSN: 0938-8990
DOI: 10.1007/s00335-014-9548-5
Arter J., Wegner M.:
Transcription factors Sox10 and Sox2 functionally interact with positive transcription elongation factor b in Schwann cells
In: Journal of Neurochemistry 132 (2015), S. 384-93
ISSN: 0022-3042
DOI: 10.1111/jnc.13013
Bischof M., Weider M., Küspert M., Nave KA., Wegner M.:
Brg1-dependent chromatin remodelling is not essentially required during oligodendroglial differentiation
In: The Journal of Neuroscience 35 (2015), S. 21-35
ISSN: 1529-2401
DOI: 10.1523/JNEUROSCI.1468-14.2015
Kim GJ., Sock E., Buchberger A., Just W., Denzer F., Hoepffner W., German J., Cole T., Mann J., Seguin JH., Zipf W., Costigan C., Schmiady H., Rostasy M., Kramer M., Kaltenbach S., Roesler B., Georg I., Troppmann E., Teichmann AC., Salfelder A., Widholz SA., Wieacker P., Hiort O., Camerino G., Radi O., Wegner M., Arnold HH., Scherer G.:
Copy number variation of two separate regulatory regions upstream of SOX9 causes isolated 46,XY or 46,XX disorder of sex development
In: Journal of Medical Genetics 52 (2015), S. 240-7
ISSN: 0022-2593
DOI: 10.1136/jmedgenet-2014-102864
Lang H., Xing Y., Brown LN., Samuvel DJ., Panganiban CH., Havens LT., Balasubramanian S., Wegner M., Krug EL., Barth JL.:
Neural stem/progenitor cell properties of glial cells in the adult mouse auditory nerve
In: Scientific Reports 5 (2015), S. 13383
ISSN: 2045-2322
DOI: 10.1038/srep13383
Quiroga AC., Stolt C., Diez Del Corral R., Dimitrov S., Perez-Alcala S., Sock E., Barbas JA., Wegner M., Morales AV.:
Sox5 controls dorsal progenitor and interneuron specification in the spinal cord
In: Developmental Neurobiology 75 (2015), S. 522-38
ISSN: 1932-8451
DOI: 10.1002/dneu.22240
Reiprich S., Wegner M.:
From CNS stem cells to neurons and glia: Sox for everyone
In: Cell and Tissue Research 359 (2015), S. 111-24
ISSN: 0302-766X
DOI: 10.1007/s00441-014-1909-6
Shakhova O., Cheng P., Mishra PJ., Zingg D., Schaefer SM., Debbache J., Haeusel J., Matter C., Guo T., Davis S., Meltzer P., Mihic-Probst D., Moch H., Wegner M., Merlino G., Levesque MP., Dummer R., Santoro R., Cinelli P., Sommer L.:
Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma
In: PLoS Genetics 11 (2015), S. e1004877
ISSN: 1553-7390
DOI: 10.1371/journal.pgen.1004877
Wegener A., Deboux C., Bachelin C., Frah M., Kerninon C., Seilhean D., Weider M., Wegner M., Nait-Oumesmar B.:
Gain of Olig2 function in oligodendrocyte progenitors promotes remyelination
In: Brain 138 (2015), S. 120-35
ISSN: 0006-8950
DOI: 10.1093/brain/awu375
Weider M., Wegener A., Schmitt-Engel C., Küspert M., Hillgaertner S., Boesl MR., Hermans-Borgmeyer I., Nait-Oumesmar B., Wegner M.:
Elevated in vivo levels of a single transcription factor directly convert satellite glia into oligodendrocyte-like cells
In: PLoS Genetics 11 (2015), S. e1005008
ISSN: 1553-7390
DOI: 10.1371/journal.pgen.1005008

Ettle B., Reiprich S., Deußer J., Schlachetzki J., Xiang W., Prots I., Masliah E., Winner B., Wegner M., Winkler J.:
Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells
In: Molecular and Cellular Neuroscience 62 (2014), S. 68-78
ISSN: 1044-7431
DOI: 10.1016/j.mcn.2014.06.012
Glasgow SM., Zhu W., Stolt C., Huang TW., Chen F., Loturco JJ., Neul JL., Wegner M., Mohila C., Deneen B.:
Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes
In: Nature Neuroscience 17 (2014), S. 1322-9
ISSN: 1097-6256
DOI: 10.1038/nn.3790
Hoffmann SA., Hos D., Küspert M., Lang RA., Lovell-Badge R., Wegner M., Reiprich S.:
Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes
In: Development 141 (2014), S. 39-50
ISSN: 1477-9129
DOI: 10.1242/dev.098418
May VEL., Ettle B., Pöhler AM., Nuber S., Ubhi K., Rockenstein E., Winner B., Wegner M., Masliah E., Winkler J.:
?-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy
In: Neurobiology of Aging 35 (2014), S. 2357-68
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2014.02.028
Paul M., Harvey RP., Wegner M., Sock E.:
Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types
In: Cellular and Molecular Life Sciences 71 (2014), S. 2931-45
ISSN: 1420-682X
DOI: 10.1007/s00018-013-1523-x
Reiprich S., Wegner M.:
Sox2: A multitasking networker.
In: Neurogenesis (2014), S. e962391
ISSN: 2326-2133
Mao Y.Y., Reiprich Simone, Wegner Michael, Fritzsch B.:
Targeted deletion of Sox10 by Wnt1-cre defects: neuronal migration and projection in the mouse inner ear.
In: PLoS ONE (2014), S. e94580
ISSN: 1932-6203
Glasgow S., Zhu W, Stolt C.C., Huang T.-E., Chen F., LoTurco J.J., Neul J.L., Wegner Michael, Mohila C., Deneen B.:
Mutual Antagonism Between Sox10 and NFIA Regulates Diversification of Glial Lineages and Glioma Sub-Types.
In: Nature Neuroscience (2014), S. 1322-1329
ISSN: 1097-6256
Winner B., May VEL., Ettle B., Pöhler AM., Nuber S., Ubhi K., Rockenstein E., Wegner M., Masliah E., Winkler J.:
α-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy.
In: Neurobiology of Aging 35 (2014), S. 2357-68
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2014.02.028
Zhu Q., Zhao X., Zheng K., Li H., Huang H., Zhang Z., Mastracci T., Wegner M., Chen Y., Sussel L., Qiu M.:
Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS
In: Development 141 (2014), S. 548-55
ISSN: 1477-9129
DOI: 10.1242/dev.095323

Barraud P., St John JA., Stolt C., Wegner M., Baker CVH.:
Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons
In: Biology Open 2 (2013), S. 750-9
ISSN: 2046-6390
DOI: 10.1242/bio.20135249
Bujalka H., Koenning M., Jackson S., Perreau VM., Pope B., Hay CM., Mitew S., Hill AF., Lu QR., Wegner M., Srinivasan R., Svaren J., Willingham M., Barres BA., Emery B.:
MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes
In: Plos Biology 11 (2013), S. e1001625
ISSN: 1544-9173
DOI: 10.1371/journal.pbio.1001625
Harris ML., Buac K., Shakhova O., Hakami RM., Wegner M., Sommer L., Pavan WJ.:
A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors
In: PLoS Genetics 9 (2013), S. e1003644
ISSN: 1553-7390
DOI: 10.1371/journal.pgen.1003644
Hornig J., Fröb F., Vogl M., Hermans-Borgmeyer I., Tamm ER., Wegner M.:
The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes
In: PLoS Genetics 9 (2013), S. e1003907
ISSN: 1553-7390
DOI: 10.1371/journal.pgen.1003907
Usui A., Mochizuki Y., Iida A., Miyauchi E., Satoh S., Sock Elisabeth, Nakauchi H., Aburatani H., Murakami A., Wegner Michael, Watanabe S.:
The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells.
In: Development (2013), S. 740-750
ISSN: 1477-9129
DOI: 10.1242/dev.090274
Trost A., Schroedl F., Lange S., Rivera FJ., Tempfer H., Korntner S., Stolt C., Wegner M., Bogner B., Kaser-Eichberger A., Krefft K., Runge C., Aigner L., Reitsamer HA.:
Neural crest origin of retinal and choroidal pericytes
In: Investigative Ophthalmology & Visual Science 54 (2013), S. 7910-21
ISSN: 0146-0404
DOI: 10.1167/iovs.13-12946
Vogl M., Reiprich S., Küspert M., Kosian T., Schrewe H., Nave KA., Wegner M.:
Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia
In: The Journal of Neuroscience 33 (2013), S. 6679-90
ISSN: 1529-2401
DOI: 10.1523/JNEUROSCI.5178-12.2013
Usui A., Iwagawa T., Mochizuki Y., Iida A., Wegner Michael, Murakami A., Watanabe S.:
Expression of Sox4 and Sox11 is regulated by multiple mechanisms during retinal development.
In: Febs Letters (2013), S. 358-363
ISSN: 0014-5793
DOI: 10.1016/j.febslet.2012.12.017
Wegner M.:
Mighty bugs: leprosy bacteria turn schwann cells into stem cells.
In: Cell (2013), S. 15-16
ISSN: 0092-8674
DOI: 10.1016/j.cell.2013.01.001
Doddrell R.D., Dun X.P., Shivane A., Feltri M.L., Wrabetz L., Wegner Michael, Sock Elisabeth, Hanemann C.O., Parkinson D.B.:
Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells.
In: Brain (2013), S. 549-563
ISSN: 0006-8950
DOI: 10.1093/brain/aws353
Weider M., Reiprich S., Wegner M.:
Sox appeal - Sox10 attracts epigenetic and transcriptional regulators in myelinating glia
In: Biological Chemistry 394 (2013), S. 1583-93
ISSN: 1431-6730
DOI: 10.1515/hsz-2013-0146

Fröb Franziska, Bremer M., Finzsch M., Kichko Tetyana, Reeh Peter W., Tamm E.R., Charnay P., Wegner Michael:
Establishment of myelinating Schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10.
In: Glia (2012), S. 806-819
ISSN: 0894-1491
DOI: 10.1002/glia.22310
Küspert Melanie, Weider Matthias, Müller Jana, Hermans-Borgmeyer I., Meijer D., Wegner Michael:
Desert Hedgehog links transcription factor Sox10 to perineurial development.
In: Journal of Neuroscience (2012), S. 5472-5480
ISSN: 0270-6474
DOI: 10.1523/jneurosci.5759-11.2012
Wahlbuhl M., Reiprich Simone, Vogl M.R., Bösl M.R., Wegner Michael:
Transcription factor Sox10 orchestrates activity of a neural crest-specific enhancer in the vicinity of its gene.
In: Nucleic Acids Research (2012), S. 88-101
ISSN: 0305-1048
DOI: 10.1093/nar/gkr734
Shakhova O., Zingg D., Schaefer S.M., Hari L., Civenni G., Blunschi J., Claudinot S., Okoniewski M., Beermann F., Mihic-Probst D., Moch H., Wegner Michael, Dummer R., Barrandon Y., Cinelli P., Sommer L.:
Sox10 promotes the formation and maintenance of giant congenital nevus and melanoma.
In: Nature Cell Biology (2012), S. 882-890
ISSN: 1465-7392
Yusuf D., Butland S.I., Swanson M.I., Bolotin E., Ticoll A., Cheung W.A., Zhang X.Y., Dickman C.T., Fulton D.L., Lim J.S., Schnabl J.M., Ramos O.H., Vasseur-Cognet M., de Leeuw C.N., Simpson E.M., Ryffel G.U., Lam E.W., Kist R., Wilson M.S., Marco-Ferreres R., Brosens J.J., Beccari L.L., Bovolenta P., Benayoun B.A., Monteiro L.J., Schwenen H.D., Grontved L., Wederell E., Mandrup S., Veitia R.A., Chakravarthy H., Hoodless P.A., Mancarelli M., Torbett B.E., Banham A.H., Reddy S.P., Cullum R.L., Liedtke M., Tschan M.P., Vaz M., Rizzino A., Zannini M., Frietze S., Farnham P.J., Eijkelenboom A., Brown P.J., Laperriere D., Leprince D., de Cristofaro T., Prince K.L., Putker M., Del Peso L., Camenich G., Wenger R.H., Mikula M., Rozendaal M., Mader S., Ostrowski J., Rhodes S.J., Van Rechem C., Boulay G., Olechnowicz S.W., Breslin M.B., Lan M.S., Nanan K.K., Wegner Michael, Hou J., Mullen R.D., Colvin S.C., Noy P.J., Webb C.F., Witek M.E., Ferrell S., Daniel J.M., Park J., Waldman S.A., Peet D.J., Taggart M., Jayaraman P.S., Karrich J.J., Blom B., Vesuna F., O´Green H., Sun Y., Gronostajski R.M., Woodcroft M.W., Hough M.R., Chen E., Europe-Finner N., Karolczak-Bayatti M., Bailey J., Hankinson O., Raman V., Lebrun D.P., Biswal S., Harvey C.J., Debruyne J.P., Hogenesch J.B., Hevner R.F., Heligon C., Luo X.M., Blank M.C., Millen K.J., Sharlin D.S., Forrest D., Dahlman-Wright K., Zhao C., Mishima Y., Sinha S., Chakrabarti R., Portales-Casamar E., Sladek F.M., Bradley P.H., Wasserman W.W.:
The Transcription Factor Encyclopedia.
In: Genome Biology (2012), S. R24
ISSN: 1474-7596
DOI: 10.1186/gb-2012-13-3-r24
Mu L., Berti L., Masserdotti G., Covic M., Michaelidis T., Doberauer K., Merz K., Rehfeld F., Haslinger A., Wegner Michael, Sock Elisabeth, Lefebvre V., Couillard-Depres S., Aigner L., Berninger B., Lie Dieter Chichung:
SoxC transcription factors are required for neuronal differentiation in adult hippocampal neurogenesis.
In: Journal of Neuroscience (2012), S. 3067-3080
ISSN: 0270-6474
DOI: 10.1523/JNEUROSCI.4679-11.2012
Weider Matthias, Küspert Melanie, Bischof Melanie, Vogl M.R., Hornig Julia, Loy Kristina, Kosian T., Müller Jana, Hillgärtner Simone, Tamm E.R., Metzger D. , Wegner Michael:
Chromatin remodelling factor Brg1 is required for Schwann cell differentiation and myelination.
In: Developmental Cell (2012), S. 193-201
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2012.05.017

Bremer M., Fröb Franziska, Kichko Tetyana, Reeh Peter W., Tamm E.R., Suter U., Wegner Michael:
Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve.
In: Glia (2011), S. 1022-1032
ISSN: 0894-1491
DOI: 10.1002/glia.21173
Küspert M., Hammer A., Bösl M., Wegner M.:
Olig2 regulates Sox10 expression in oligodendrocyte precursors through an evolutionary conserved distal enhancer.
In: Nucleic Acids Research (2011), S. 1280-1293
ISSN: 0305-1048
DOI: 10.1093/nar/gkq951
Lin L., Lee V.M., Wang Y., Lin J.S., Sock Elisabeth, Wegner Michael, Lei L.:
Sox11 regulates survival and axonal growth of embryonic sensory neurons.
In: Developmental Dynamics (2011), S. 52-64
ISSN: 1058-8388
DOI: 10.1002/dvdy.22489
Reginensi A., Clarkson M., Neirijnck Y., Lu B., Ohyama T., Groves A.K., Sock Elisabeth, Wegner Michael, Costantini F., Chaboissier M.C., Schedl A.:
SOX9 controls epithelial branching by activating RET effector genes during kidney development.
In: Human Molecular Genetics (2011), S. 1143-1153
ISSN: 0964-6906
DOI: 10.1093/hmg/ddq558
Gallenberger M., Meinel D., Kroeber M., Wegner Michael, Milkereit P., Bösl M.R., Tamm E.R.:
Lack of Wdr36 leads to preimplantation embryonic lethality in mice and delays the formation of small subunit ribosomal RNA in human cells in vitro.
In: Human Molecular Genetics (2011), S. 422-435
ISSN: 0964-6906
DOI: 10.1093/hmg/ddq478
Wegner M.:
SOX after SOX: SOXession regulates neurogenesis.
In: Genes & Development (2011), S. 2423-24-28
ISSN: 0890-9369
DOI: 10.1101/gad.181487.111
John N., Cinelli P., Wegner Michael, Sommer L.:
Transforming Growth Factor β-Mediated Sox10 Suppression Controls Mesenchymal Progenitor Generation in Neural Crest Stem Cells.
In: Stem cells (2011), S. 689-699
ISSN: 0250-6793
DOI: 10.1002/stem.607

Thein D.C., Thalhammer J.M., Hartwig Anna, Crenshaw III E.B., Lefebvre V., Wegner Michael, Sock Elisabeth:
The closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord development.
In: Journal of neurochemistry (2010), S. 131-141
ISSN: 1471-4159
DOI: 10.1111/j.1471-4159.2010.06910.x
Cossais Francois, Wahlbuhl Mandy, Müller Jana, Wegner Michael:
SOX10 structure function analysis in the chicken reveals important insights into its role in human neurocristopathies.
In: Human Molecular Genetics (2010), S. 2409-2420
ISSN: 0964-6906
Reiprich Simone, Müller Jana, Schreiner S., Wegner Michael:
Activation of Krox20 gene expression by Sox10 in myelinating Schwann cells.
In: Journal of Neurochemistry (2010), S. 744-754
ISSN: 0022-3042
DOI: 10.1111/j.1471-4159.2009.06498.x
Guth S.I.E., Bösl M.R., Sock Elisabeth, Wegner Michael:
Evolutionary conserved sequence elements with embryonic enhancer activity in the vicinity of the mammalian Sox8 gene.
In: International Journal of Biochemistry & Cell Biology (2010), S. 465-471
ISSN: 1357-2725
DOI: 10.1016/j.biocel.2009.07.008
Bhattaram P., Penzo-Mendez A., Sock Elisabeth, Colmenares C., Kaneko K.J., Vassilev A., DePamphilis M.L., Wegner Michael, Lefebvre V.:
Organogenesis relies on Sox4, Sox11, and Sox12 for survival of neural and mesenchymal progenitor cells.
In: Nature Communications (2010), S. 9
ISSN: 2041-1723
Cossais Francois, Sock Elisabeth, Hornig J., Schreiner S., Kellerer S., Bösl M.R., Russel S., Wegner Michael:
Replacement of mouse Sox10 by the Drosophila ortholog Sox100B provides evidence for co-option of SoxE proteins into vertebrate-specific gene-regulatory networks through altered expression.
In: Developmental Biology (2010), S. 267-281
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2010.01.038
Breuskin I., Bodson M., Thelen N., Thiry M., Borgs L., Nguyen L., Stolt Claus, Wegner Michael, Lefebvre P.P., Malgrange B.:
Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10.
In: Journal of Neurochemistry (2010), S. 1827-1839
ISSN: 0022-3042
DOI: 10.1111/j.1471-4159.2010.06897.x
Stolt C., Wegner M.:
SoxE function in vertebrate nervous system development.
In: International Journal of Biochemistry & Cell Biology (2010), S. 437-440
ISSN: 1357-2725
DOI: 10.1016/j.biocel.2009.07.014
Wegner M.:
All purpose SOX: The many roles of Sox proteins in gene expression.
In: International Journal of Biochemistry & Cell Biology (2010), S. 381-390
ISSN: 1357-2725
DOI: 10.1016/j.biocel.2009.07.006
Staffler A., Hammel M., Wahlbuhl Mandy, Bidlingmaier C., Flemmer A.W., Pagel P., Nicolai T., Wegner Michael, Holzinger A.:
Heterozygous SOX9 mutations allowing for residual DNA-binding and transcriptional activation lead to the acampomelic variant of Campomelic Dysplasia.
In: Human Mutation (2010), S. E1436-1444
ISSN: 1059-7794
DOI: 10.1002/humu.21238
Kanykina N., Abelson K., King D., Liakhovitskaia A., Schreiner S., Wegner Michael, Kozlova E.N.:
In vitro and in vivo effects on neural crest stem cell differentiation by conditional activation of Runx1 short isoform and its effect on neuropathic pain behaviour.
In: Upsala Journal of Medical Sciences (2010), S. 56-64
ISSN: 0300-9734
DOI: 10.3109/03009730903572065
Wallace A., Schmidt C., Schachner M., Wegner Michael, Anderson R.:
L1cam acts as a modifier gene during enteric nervous system development.
In: Neurobiology of Disease (2010), S. 622-633
ISSN: 0969-9961
DOI: 10.1016/j.nbd.2010.08.006
Park J., Zhang J.J.R., Moro A., Kushida M., Wegner Michael, Kim P.C.W.:
Regulation of Sox9 by Sonic Hedgehog (Shh) is essential for patterning and formation of tracheal cartilage.
In: Developmental Dynamics (2010), S. 514-526
ISSN: 1058-8388
DOI: 10.1002/dvdy.22192
Finzsch M., Schreiner S., Kichko T., Reeh R., Tamm E.R., Bösl M.R., Meijer D., Wegner Michael:
Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage.
In: The Journal of Cell Biology (2010), S. 701-712
ISSN: 0021-9525
DOI: 10.1083/jcb.200912142
Potzner M.R., Tsarovina K., Binder E., Penzo-Méndez A., Lefebvre V., Rohrer H., Wegner Michael, Sock Elisabeth:
Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system.
In: Development (2010), S. 775-784
ISSN: 1477-9129
DOI: 10.1242/dev.042101

Wolf M., Lommes P., Sock Elisabeth, Reiprich Simone, Friedrich R.P., Müller Jana, Stolt Claus, Bermingham J.R., Wegner Michael:
Replacement of related POU transcription factors leads to severe defects in mouse forebrain development.
In: Developmental Biology (2009), S. 418-428
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2009.06.011
Guth S.I.E., Schmidt K., Hess A., Wegner Michael:
Adult-onset degeneration of adipose tissue in mice deficient for the Sox8 transcription factor.
In: Journal of Lipid Research (2009), S. 1269-1280
ISSN: 0022-2275
DOI: 10.1194/jlr.M800531-JLR200
Aldskogius H., Berens C., Kanaykina N., Liakhovitskaia A., Medvinsky A., Sandelin M., Schreiner S., Wegner Michael, Hjerling-Leffler J., Kozlova E.N.:
Regulation of Boundary Cap Neural Crest Stem Cell Differentiation after Transplantation.
In: Stem cells (2009), S. 1592-1603
ISSN: 0250-6793
DOI: 10.1002/stem.77
Barrionuevo F., Georg I., Scherthan H., Lécureuil C., Guillou F., Wegner Michael, Scherer G.:
Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8.
In: Developmental Biology (2009), S. 301-312
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2008.12.011
Batista-Brito R., Rossignol E., Hjerling-Leffler J., Denaxa M., Wegner Michael, Lefebvre V., Pachnis V., Fishell G.:
The cell-intrinsic requirement of Sox6 for cortical interneuron development.
In: Neuron (2009), S. 466-481
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2009.08.005

Reiprich Simone, Stolt Claus, Schreiner S., Parlato R., Wegner Michael:
SoxE proteins are differentially required in mouse adrenal gland development.
In: Molecular Biology of the Cell (2008), S. 1575-1586
ISSN: 1059-1524
DOI: 10.1091/mbc.E07-08-0782
Wurm A., Sock Elisabeth, Fuchshofer R., Wegner Michael, Tamm E.R.:
Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11.
In: Experimental Eye Research (2008), S. 895-907
ISSN: 0014-4835
DOI: 10.1016/j.exer.2008.03.004
Stolt Claus, Lommes P., Hillgärtner Simone, Wegner Michael:
The transcription factor Sox5 modulates Sox10 function during melanocyte development.
In: Nucleic Acids Research (2008), S. 5427-5440
ISSN: 0305-1048
DOI: 10.1093/nar/gkn527
Müller S.M., Stolt Claus, Terszowski G., Blum C., Amagai T., Kessaris N., Iannarelli P., Richardson W.D., Wegner Michael, Rodewald H.R.:
Neural crest origin of perivascular mesenchyme in the adult thymus.
In: Journal of Immunology (2008), S. 5344-5351
ISSN: 0022-1767
Finzsch Markus, Stolt Claus, Lommes P., Wegner Michael:
Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression.
In: Development (2008), S. 637-646
ISSN: 1477-9129
DOI: 10.1242/dev.010454
Wegner M.:
A matter of identity: transcriptional control in oligodendrocytes.
In: Journal of Molecular Neuroscience (2008), S. 3-12
ISSN: 0895-8696
Aquino J.B., Marmigere F., Lallemend F., Lundgren T.K., Villar M.J., Wegner Michael, Ernfors P.:
Differential expression and dynamic changes of murine NEDD9 in progenitor cells of diverse tissues.
In: Gene Expression Patterns (2008), S. 217-226
ISSN: 1567-133X
DOI: 10.1016/j.gep.2008.01.001
Guth S.I.E., Wegner Michael:
Having it both ways: Sox protein function between conservation and innovation.
In: Cellular and Molecular Life Sciences (2008), S. 3000-3018
ISSN: 1420-682X
DOI: 10.1007/s00018-008-8138-7
Hoff S., Zeller F., Hann von Weyern C.W., Wegner Michael, Schemann M., Michel K., Rühl A.:
Quantitative assessment of glial cells in the human and guinea pig enteric nervous system with an anti-Sox8/9/10 antibody.
In: Journal of Comparative Neurology (2008), S. 356-371
ISSN: 0021-9967
DOI: 10.1002/cne.21769
Wang H., Leav I., Ibaragi S., Wegner Michael, Hu G.F., Lu M., Balk S., Yuan X.:
SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion.
In: Cancer Research (2008), S. 1625-1630
ISSN: 0008-5472
DOI: 10.1158/0008-5472.CAN-07-5915
Hoser M., Potzner M.R., Koch J.M.C., Bösl M.R., Wegner Michael, Sock Elisabeth:
Sox12 deletion in the mouse reveals non-reciprocal redundancy with the related Sox4 and Sox11 transcription factors.
(2008), S. 4675-4687

Hoser M. , Baader S.L., Bösl M.R., Ihmer A., Wegner Michael, Sock Elisabeth:
Prolonged glial expression of Sox4 in the central nervous system leads to architectural cerebellar defects and ataxia.
In: The Journal of Neuroscience (2007), S. 5495-5505
ISSN: 1529-2401
Schlierf B., Friedrich R.P., Felsberg J., Reifenberger G., Wegner Michael:
Expression of SoxE and SoxD genes in human gliomas.
In: Neuropathology and Applied Neurobiology (2007), S. 621-630
ISSN: 0305-1846
DOI: 10.1111/j.1365-2990.2007.00881.x
Liu Z., Hu X., Cai J., Liu B., Peng X., Wegner Michael, Qiu M.:
Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms.
In: Developmental Biology (2007), S. 683-693
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2006.10.007
Werner T., Hammer A., Wahlbuhl Mandy, Bösl Michael, Wegner Michael:
Multiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis.
In: Nucleic Acids Research (2007), S. 6526-6538
ISSN: 0305-1048
DOI: 10.1093/nar/gkm727
Inoue K., Ohyama T., Sakuragi Y., Li-Hua Y., Yamamoto R., Yu L.-H., Goto Y-i., Wegner Michael, Lupski J.R.:
Translation of SOX10 3' untranslated region causes a complex severe neurocristopathy by generation of a deleterious functional domain.
In: Human Molecular Genetics (2007), S. 3037-3046
ISSN: 0964-6906
DOI: 10.1093/hmg/ddm262
Schreiner S., Cossais Francois, Fischer K., Scholz S., Bösl Rebecca, Holtmann B., Sendtner M., Wegner Michael:
Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages.
In: Development (2007), S. 3271-3281
ISSN: 1477-9129
DOI: 10.1242/dev.003350

Stolt Claus, Schlierf A., Lommes Petra, Hillgärtner S., Werner T., Kosian T., Sock Elisabeth, Kessaris N., Richardson W.D., Lefebre V., Wegner Michael:
SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function.
In: Developmental Cell (2006), S. 697-709
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2006.08.011
Kessaris N., Fogarty M., Iannarelli P., Grist M., Wegner Michael, Richardson W.D.:
Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an early embryonic lineage.
In: Nature Neuroscience (2006), S. 173-179
ISSN: 1097-6256
Ito Y., Wiese S., Chittka A., Rossol W., Bömmel H., Watabe K., Wegner Michael, Sendtner M.:
Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells.
In: Proceedings of the National Academy of Sciences of the United States of America (2006), S. 7871-7876
ISSN: 0027-8424
DOI: 10.1073/pnas.0602332103
Wißmüller S., Kosian T., Wolf Matthias, Wegner Michael:
The High-mobility-group domain of Sox proteins interacts with the DNA-binding domains of many transcription factors.
In: Nucleic Acids Research (2006), S. 1735-1744
ISSN: 0305-1048
DOI: 10.1093/nar/gkl105
Marmigere F., Montelius A., Wegner Michael, Groner Y., Reichardt L.F., Ernfors P.:
The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons.
In: Nature Neuroscience (2006), S. 180-187
ISSN: 1097-6256
DOI: 10.1038/nn1631
Schlierf Beate, Werner T., Glaser Gabriele, Wegner Michael:
Expression of Connexin47 in oligodendrocytes is regulated by the Sox10 transcription factor.
In: Journal of Molecular Biology (2006), S. 11-21
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2006.05.072
Bannykh S.I., Stolt Claus, Kim J., Perry A., Wegner Michael:
Oligodendroglial-specific transcriptional factor SOX10 is ubiquitously expressed in human gliomas.
In: Journal of Neuro-Oncology (2006), S. 115-127
ISSN: 0167-594X
Kellerer S., Schreiner Silke, Stolt Claus, Scholz Sebastian, Bösl M.R., Wegner Michael:
Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence.
In: Development (2006), S. 2875-286
ISSN: 1477-9129
DOI: 10.1242/dev.02477

Schmidt K., Schinke T., Haberland M., Priemel M., Schilling A.F., Mueldner C., Rueger J.M., Sock Elisabeth, Wegner Michael, Amling M.:
The high-mobility-group transcription factor Sox8 is a negative regulator of osteoblast differentiation.
In: The Journal of Cell Biology (2005), S. 899-910
ISSN: 0021-9525
DOI: 10.1083/jcb.200408013
Baranek C., Sock Elisabeth, Wegner Michael:
The POU protein Oct-6 is a nucleocytoplasmic shuttling protein.
In: Nucleic Acids Research (2005), S. 6277-6286
ISSN: 0305-1048
DOI: 10.1093/nar/gki947
Stolt Claus, Schmitt S., Lommes Petra, Sock Elisabeth, Wegner Michael:
Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord.
In: Developmental Biology (2005), S. 309-317
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2005.03.010
Wegner M.:
Secrets to a healthy Sox life: Lessons for melanocytes.
In: Pigment Cell Research (2005), S. 74-85
ISSN: 0893-5785
DOI: 10.1111/j.1600-0749.2005.00218.x
Friedrich R.P., Schlierf Beate, Tamm E.R., Bösl M.R., Wegner Michael:
The class III POU domain protein Brn-1 can fully replace the related Oct-6 during Schwann cell development and myelination.
In: Molecular and Cellular Biology (2005), S. 1821-1829
ISSN: 0270-7306
DOI: 10.1128/MCB.25.5.1821-1829.2005
Schlierf Beate, Lang Stefan, Kosian T., Werner Thomas, Wegner Michael:
The high-mobility group transcription factor Sox10 interacts with the N-myc interacting protein Nmi.
In: Journal of Molecular Biology (2005), S. 1033-1042
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2005.09.013
Thomee C., Schubert S.W., Parma J., Le P.Q., Hashemolhosseini Said, Wegner Michael, Abramowicz M.J.:
GCMB mutation in familial isolated hypo-parathyroidism with residual secretion of parathyroid hormone.
In: Journal of Clinical Endocrinology and Metabolism (2005), S. 2487-2492
ISSN: 0021-972X
Wegner M., Stolt C.:
From stem cells to neurons and glia: a soxist's view of neural development.
In: Trends in Neurosciences (2005), S. 583-588
ISSN: 0166-2236
DOI: 10.1016/j.tins.2005.08.008
Maka Marzena, Stolt Claus, Wegner Michael:
Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect.
In: Developmental Biology (2005), S. 155-169
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2004.09.014

Sock Elisabeth, Rettig S.D., Enderich J., Bösl M.R., Tamm E.R., Wegner Michael:
Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling.
In: Molecular and Cellular Biology (2004), S. 6635-6644
ISSN: 0270-7306
DOI: 10.1128/MCB.24.15.6635-6644.2004
Ludwig Andreas, Schlierf Beate, Schardt A., Nave K.A., Wegner Michael:
A Sox10 rtTA mouse line for tetracycline-inducible expression of transgenes in neural crest cells and oligodendrocytes.
In: Genesis (2004), S. 171-175
ISSN: 1526-954X
Chaboissier M.-C., Kobayashi A., Vidal V.I.P., Lützkendorf S., van de Kant H.J.G., Wegner Michael, de Rooij D.G., Behringer R.R., Schedl A.:
Functional analysis of Sox8 and Sox9 during sex determination in the mouse.
In: Development (2004), S. 1891-1901
ISSN: 1477-9129
DOI: 10.1242/dev.01087
Schubert S.W., Kardash E., Khan M.A., Cheusova T., Kilian K., Wegner Michael:
Interaction, Cooperative Promoter Modulation and Renal Colocalisation of GCMa and Pitx2.
In: Journal of Biological Chemistry (2004), S. 50358-50365
ISSN: 0021-9258
Ludwig A., Rehberg S., Wegner Michael:
Melanocyte-Specific Expression Of Dopachrome Tautomerase Is Dependent On Synergistic Gene Activation By The Sox10 And Mitf Transcription Factors.
In: Febs Letters (2004), S. 236-244
ISSN: 0014-5793
DOI: 10.1016/S0014-5793(03)01446-7
Inoue K., Khajavi M., Ohyama T., Hirabayashi S.-I., Wilson J., Reggin J.D., Mancias P., Butler I.J., Wilkinson M.F., Wegner Michael, Lupski J.R.:
Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations.
In: Nature Genetics (2004), S. 361-369
ISSN: 1061-4036
DOI: 10.1038/ng1322
Hashemolhosseini Said, Schmidt K., Kilian K., Rodriguez E., Wegner Michael:
Conservation and variation of structure and function in a newly identified GCM homolog from chicken
In: Journal of Molecular Biology (2004), S. 441-451
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2003.12.029
Wegner M., Hashemolhosseini S.:
Impacts of a new trancription factor family: Mammalian GCM proteins in health and disease.
In: The Journal of Cell Biology (2004), S. 765-768
ISSN: 0021-9525
Stolt Claus, Lommes Petra, Friedrich R.P., Wegner Michael:
Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy.
In: Development (2004), S. 2349-2358
ISSN: 1477-9129
DOI: 10.1242/dev.01114

Sock Elisabeth, Pagon Roberta A., Keymolen Kathelijn, Lissens Willy, Wegner Michael, Scherer Gerd:
Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia
In: Human Molecular Genetics 12 (2003), S. 1439-1447
ISSN: 0964-6906
Stolt Claus, Lommes Petra, Sock Elisabeth, Chaboissier M.-C., Schedl A., Wegner Michael:
The Sox9 transcription factor determines glial fate choice in the developing spinal cord.
In: Genes & Development (2003), S. 1677-1689
ISSN: 0890-9369
DOI: 10.1101/gad.259003
Huber W.E., Price R., Widlund H.R., Du J., Davis I.J., Wegner Michael, Fisher D.E.:
A tissue restricted cAMP transcriptional response: SOX10 modulates MSH-triggered expression of MITF in melanocytes.
In: Journal of Biological Chemistry (2003), S. 45224-45230
ISSN: 0021-9258
Lioubinski O, Müller M, Wegner Michael, Sander Manfred:
Expression of Sox transcription factors in the developing mouse pancreas.
In: Developmental Dynamics (2003), S. 402-408
ISSN: 1058-8388
DOI: 10.1002/dvdy.10311
Schmidt Katy, Glaser Gabriele, Wernig Anton, Wegner Michael, Rosorius Olaf:
Sox8 is a specific marker for muscle satellite cells and inhibits myogenesis
In: Journal of Biological Chemistry (2003), S. 29769-29775
ISSN: 0021-9258
DOI: 10.1074/jbc.M301539200
Cohen Serge X., Moulin Martine, Hashemolhosseini Said, Kilian Karin, Wegner Michael, Müller Christoph W.:
Structure of the GCM domain-DNA complex: a DNA-binding domain with a novel fold and mode of target site recognition
In: EMBO Journal 22 (2003), S. 1835-45
ISSN: 0261-4189
DOI: 10.1093/emboj/cdg182

Hashemolhosseini S., Hadjihannas M., Haase C., Amann KU., Wegner M.:
Restricted expression of mGCMa in kidney ind thymus
In: Mechanisms of Development (2002), S. in press
ISSN: 0925-4773
Hashemolhosseini Said, Hadjihannas Michel, Stolt Claus, Haas Christian, Amann Kerstin U., Wegner Michael:
Restricted expression of mouse GCMa/Gcm1 in kidney and thymus
In: Mechanisms of Development 118 (2002), S. 175-178
ISSN: 0925-4773
DOI: 10.1016/S0925-4773(02)00239-3
Schlierf Beate, Ludwig Andreas, Klenovsek Karin, Wegner Michael:
Cooperative binding of Sox10 to DNA: requirements and consequences
In: Nucleic Acids Research 30 (2002), S. 5509-5516
ISSN: 0305-1048
DOI: 10.1093/nar/gkf690
Cohen Serge X., Moulin Martine, Schilling Oliver, Meyer-Klaucke Wolfram, Schreiber Jörg, Wegner Michael, Müller Christoph W.:
The GCM domain is a Zn-coordinating DNA-binding domain
In: Febs Letters 528 (2002), S. 95-100
ISSN: 0014-5793
DOI: 10.1016/S0014-5793(02)03257-X
Rehberg Stephan, Lischka Peter, Glaser Gabriele, Stamminger Thomas, Wegner Michael, Rosorius Olaf:
Sox10 is an active nucleocytoplasmic shuttle protein, and shuttling is crucial for Sox10-mediated transactivation
In: Molecular and Cellular Biology 22 (2002), S. 5826-5834
ISSN: 0270-7306
DOI: 10.1128/MCB.22.16.5826-5834.2002
Stolt Claus, Rehberg Stephan, Ader Marius, Lommes Petra, Riethmacher Dieter, Schachner Melitta, Bartsch Udo, Wegner Michael:
Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10
In: Genes & Development 16 (2002), S. 165-170
ISSN: 0890-9369
DOI: 10.1101/gad.215802

Sock Elisabeth, Schmidt Katy, Hermanns-Borgmeyer Irm, Bösl Michael, Wegner Michael:
Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8
In: Molecular and Cellular Biology 21 (2001), S. 6951-6959
ISSN: 0270-7306
DOI: 10.1128/MCB.21.20.6951-6959.2001
Wegner Michael, Riethmacher Dieter:
Chronicles of a switch hunt: gcm genes in development
In: Trends in Genetics 17 (2001), S. 286-90
ISSN: 0168-9525
DOI: 10.1016/S0168-9525(01)02275-2
Wegner M.:
Expression of transcription factors during oligodendroglial development
In: Microscopy Research and Technique 52 (2001), S. 746-752
ISSN: 1059-910X
DOI: 10.1002/jemt.1059
Paratore Christian, Goerich Derk E., Suter Ueli, Wegner Michael, Sommer Lukas:
Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signaling
In: Development 128 (2001), S. 3949-3961
ISSN: 1477-9129
Britsch Stefan, Goerich Derk, Riethmacher Dieter, Peirano Reto, Rossner Moritz, Nave Klaus-Armin, Birchmeier Carmen, Wegner Michael:
The transcription factor Sox10 is a key regulator of peripheral glial development
In: Genes & Development 15 (2001), S. 66-78
ISSN: 0890-9369
DOI: 10.1101/gad.186601
Sonnenberg-Riethmacher Eva, Miehe Michaela, Stolt Claus, Goerich Derk, Wegner Michael, Riethmacher Dieter:
Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10
In: Mechanisms of Development 109 (2001), S. 253-265
ISSN: 0925-4773
DOI: 10.1016/S0925-4773(01)00547-0

Bondurand Nadège, Pingault Véronique, Goerich Derk, Lemort Nicole, Sock Elisabeth, Le Caignec Cedric, Wegner Michael, Goossens Michel:
Interaction among SOX10, PAX3 and MITF, three genes altered in Waardenburg syndrome
In: Human Molecular Genetics 9 (2000), S. 1907-1917
ISSN: 0964-6906
Baumeister Hans, Wegner Michael, Richter Dietmar, Meyerhof Wolfgang:
Dual regulation of somatostatin receptor subtype 1 gene expression by pit-1 in anterior pipuitary GH3 cells
In: Molecular Endocrinology 14 (2000), S. 255-71
ISSN: 0888-8809
Winklhofer Konstanze, Albrecht Ingrid, Wegner Michael, Heilbronn Regine:
Human cytomegalovirus immediate-early gene 2 expression leads to JCV replication in nonpermissive cells via transcriptional activation of JCV T antigen
In: Virology 275 (2000), S. 323-334
ISSN: 0042-6822
DOI: 10.1006/viro.2000.0503
Schreiber Jörg, Riethmacher-Sonnenberg Eva, Riethmacher Dieter, Tuerk Elisabeth, Enderich Janna, Bösl Michael, Wegner Michael:
Placental failure in mice lacking the mammalian homolog of glial cells missing, GCMa
In: Molecular and Cellular Biology 20 (2000), S. 2466-2474
ISSN: 0270-7306
DOI: 10.1128/MCB.20.7.2466-2474.2000
Tuerk Elisabeth, Schreiber Jörg, Wegner Michael:
Protein stability and domain topology determine the transcriptional activity of the mammalian glial cells missing homolog, GCMb
In: Journal of Biological Chemistry 275 (2000), S. 4774-82
ISSN: 0021-9258
DOI: 10.1074/jbc.275.7.4774
Peirano Reto, Goerich Derk, Riethmacher Dieter, Wegner Michael:
Protein zero Gene expression is regulated by the glial transcription factor Sox10
In: Molecular and Cellular Biology 20 (2000), S. 3198-3209
ISSN: 0270-7306
DOI: 10.1128/MCB.20.9.3198-3209.2000
Peirano Reto, Wegner Michael:
The glial transcription factor Sox10 binds to DNA both as monomer and dimer with different functional consequences
In: Nucleic Acids Research 28 (2000), S. 3047-3055
ISSN: 0305-1048
Wegner M.:
Transcriptional control in myelinating glia: flavors and spices
In: Glia 31 (2000), S. 1-14
ISSN: 0894-1491
DOI: 10.1002/(SICI)1098-1136(200007)31:13.0.CO;2-V
Wegner M.:
Transcriptional control in myelinating glia: the basic recipe
In: Glia 29 (2000), S. 118-23
ISSN: 0894-1491
DOI: 10.1002/(SICI)1098-1136(20000115)29:23.0.CO;2-Q

Sock Elisabeth, Enderich Janna, Wegner Michael:
The J domain of papovaviral large tumor antigen is required for synergistic interaction with the POU-domain protein Tst-1/Oct6/SCIP
In: Molecular and Cellular Biology 19 (1999), S. 2455-2464
ISSN: 0270-7306
Vollgraf Ulrich, Wegner Michael, Richter-Landsberg Christiane:
Activation of AP-1 and NF-kappa B transcription factors is involved in hydrogen peroxide-induced apoptopic cell death of oligodendrocytes
In: Journal of Neurochemistry 73 (1999), S. 2501-2509
ISSN: 0022-3042
Bondurand Nadége, Kuhlbrodt Kirsten, Pingault Véronique, Enderich Janna, Sajus Marc, Tommerup Niels, Warburg Mette, Hennekam Raoul, Read Andrew, Wegner Michael, Goossens Michel:
A molecular analysis of the Yemenite deaf-blind hypopigmentation syndrome: Sox10 dysfunction causes different neurocristopathies
In: Human Molecular Genetics 8 (1999), S. 1785-1789
ISSN: 0964-6906
DOI: 10.1093/hmg/8.9.1785
Schneider Carolin, Wicht Helmut, Enderich Janna, Wegner Michael, Rohrer Hermann:
Bone morphogenetic proteins are required in vivo for the generation of sympathetic neurons
In: Neuron 24 (1999), S. 861-870
ISSN: 0896-6273
Wegner M.:
From head to toes: the multiple facets of Sox proteins
In: Nucleic Acids Research 27 (1999), S. 1409-1420
ISSN: 0305-1048
DOI: 10.1093/nar/27.6.1409
Reifegerst Rita, Schreiber Jörg, Gülland Sven, Lüdemann Anja, Wegner Michael:
mGCMa is a murine transcription factor that overrides cell fate decisions in Drosophila
In: Mechanisms of Development 82 (1999), S. 141-150
ISSN: 0925-4773
DOI: 10.1016/S0925-4773(99)00027-1

Kuhlbrodt Kirsten, Herbarth Beate, Sock Elisabeth, Enderich Janna, Hermans-Borgmeyer Irm, Wegner Michael:
Cooperative function of POU proteins and SOX proteins in glial cells
In: Journal of Biological Chemistry 273 (1998), S. 16050-16057
ISSN: 0021-9258
DOI: 10.1074/jbc.273.26.16050
Kuhlbrodt Kirsten, Schmidt Claudia, Sock Elisabeth, Pingault Veronique, Bondurand Nadege, Goossens Michel, Wegner Michael:
Functional analysis of Sox10 mutations found in human Waardenburg-Hirschsprung patients
In: Journal of Biological Chemistry 273 (1998), S. 23033-23038
ISSN: 0021-9258
DOI: 10.1074/jbc.273.36.23033
Kuhlbrodt Kirsten, Herbarth Beate, Sock Elisabeth, Hermans-Borgmeyer Irm, Wegner Michael:
Sox10, a novel transcriptional modulator in glial cells
In: Journal of Neuroscience 18 (1998), S. 237-250
ISSN: 0270-6474
Herbarth Beate, Meissner Hildegard, Westphal Manfred, Wegner Michael:
Absence of polyomavirus JC in glial brain tumors and glioma-derived cell lines
In: Glia 22 (1998), S. 415-420
ISSN: 0894-1491
DOI: 10.1002/(SICI)1098-1136(199804)22:43.0.CO;2-Z
Staib Caroline, Wegner Michael, Grummt Friedrich:
Activation of SV40 DNA replication in vivo by amplification-promoting sequences of the mouse ribosomal gene cluster
In: Chromosoma 107 (1998), S. 33-38
ISSN: 0009-5915
Bondurand Nadege, Kobetz Alexandra, Pingault Veronique, Lemort Nicole, Encha-Razavi Ferechte, Couly Gerard, Goerich Derk, Wegner Michael, Abitbol Marc, Goossens Michel:
Expression of Sox10 gene during human development
In: Febs Letters 432 (1998), S. 168-172
ISSN: 0014-5793
DOI: 10.1016/S0014-5793(98)00843-6
von der Kammer Heinz, Mayhaus Manuel, Albrecht Claudia, Enderich Janna, Wegner Michael, Nitsch Roger:
Muscarinic acetylcholine receptors activate expression of the EGr gene family of transcription factors
In: Journal of Biological Chemistry 273 (1998), S. 14538-14544
ISSN: 0021-9258
DOI: 10.1074/jbc.273.23.14538
Nitsch Roger, Rossner Stefan, Albrecht Claudia, Mayhaus Manuel, Enderich Janna, Schliebs Reinhard, Wegner Michael, Arendt Thomas, von der Kammer Heinz:
Muscarinic acetylcholine receptors activate the acetylcholinesterase gene promoter
In: Journal of Physiology-Paris 92 (1998), S. 257-264
ISSN: 0928-4257
DOI: 10.1016/S0928-4257(98)80029-6
Herbarth Beate, Pingault Veronique, Bondurand Nadege, Kuhlbrodt Kirsten, Hermans-Borgmeyer Irm, Puliti Aldamaria, Lemort Nicole, Goossens Michel, Wegner Michael:
Mutation of the Sry-related Sox10 gene in Dominat megacolon, a mouse model for human Hirschsprung disease
In: Proceedings of the National Academy of Sciences of the United States of America 95 (1998), S. 5161-5165
ISSN: 0027-8424
Pingault Véronique, Bondurand Nadège, Kuhlbrodt Kirsten, Goerich Derk E., Préhu Marie-Odette, Puliti Aldamaria, Herbarth Beate, Hermans-Borgmeyer Irm, Legius Eric, Matthijs Gert, Amiel Jeanne, Lyonnet Stanislas, Ceccherini Isabella, Romeo Giovanni, Smith Jill Clayton, Read Andrew P., Wegner Michael, Goossens Michel:
SOX10 mutations in patients with Waardenburg-Hirschsprung disease
In: Nature Genetics 18 (1998), S. 171-173
ISSN: 1061-4036
DOI: 10.1038/ng0298-171
Schreiber Jörg, Enderich Janna, Wegner Michael:
Structural requirements for DNA binding of GCM proteins
In: Nucleic Acids Research 26 (1998), S. 2337-2343
ISSN: 0305-1048
DOI: 10.1093/nar/26.10.2337

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