Publikationen
- Devitt L., Westphal D., Pieger K., Schneider N., Boßerhoff AK., Kuphal S.:
NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma
In: Cell Communication and Signaling 22 (2024), Art.Nr.: 256
ISSN: 1478-811X
DOI: 10.1186/s12964-024-01632-8
- Kluge V., Kappelmann-Fenzl M., Fischer S., Zimmermann T., Pommer M., Kuphal S., Boßerhoff AK.:
Alternative Wnt-signaling axis leads to a break of oncogene-induced senescence
In: Cell Death & Disease 15 (2024), Art.Nr.: 166
ISSN: 2041-4889
DOI: 10.1038/s41419-024-06550-8
- Lämmerhirt L., Kappelmann-Fenzl M., Fischer S., Meier P., Stäbler S., Kuphal S., Boßerhoff AK.:
Loss of miR-101-3p in melanoma stabilizes genomic integrity, leading to cell death prevention
In: Cellular & Molecular Biology Letters 29 (2024), Art.Nr.: 29
ISSN: 1425-8153
DOI: 10.1186/s11658-024-00552-2
- Stäbler S., Hoechst S., Thongmao A., Schneider N., Boßerhoff AK., Kuphal S.:
The Role of T-Cadherin (CDH13) in Treatment Options with Garcinol in Melanoma
In: Cancers 16 (2024), Art.Nr.: 1853
ISSN: 2072-6694
DOI: 10.3390/cancers16101853
- Heppt M., Wessely A., Hornig E., Kammerbauer C., Graf S., Besch R., French LE., Kuphal S., Kappelmann-Fenzl M., Boßerhoff AK., Berking C.:
HDAC2 is involved in the regulation of Brn3a in melanocytes and melanoma
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2023
- Heppt M., Wessely A., Hornig E., Kammerbauer C., Graf SA., Besch R., French LE., Matthies AO., Kuphal S., Kappelmann-Fenzl M., Boßerhoff AK., Berking C.:
HDAC2 Is Involved in the Regulation of BRN3A in Melanocytes and Melanoma
In: International Journal of Molecular Sciences 23 (2022), Art.Nr.: 849
ISSN: 1422-0067
DOI: 10.3390/ijms23020849
- Kluge V., Zimmermann T., Pommer M., Kuphal S., Boßerhoff AK.:
Molecular mechanisms of OIS breakdown in the context of melanoma formation
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2022
- Lämmerhirt L., Kappelmann-Fenzl M., Fischer S., Pommer M., Zimmermann T., Kluge V., Matthies AO., Kuphal S., Boßerhoff AK.:
Knockdown of Lamin B1 and the Corresponding Lamin B Receptor Leads to Changes in Heterochromatin State and Senescence Induction in Malignant Melanoma
In: Cells 11 (2022), Art.Nr.: 2154
ISSN: 2073-4409
DOI: 10.3390/cells11142154
- Lämmerhirt L., Pommer M., Zimmermann T., Kluge V., Kuphal S., Boßerhoff AK.:
The Nuclear Envelope Proteins LMNB1 and LBR influence the Chromatin Structure and Senescence Processes in Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2022
- Rachinger N., Mittag N., Böhme-Schäfer I., Xiang W., Kuphal S., Boßerhoff AK.:
Alpha-Synuclein and Its Role in Melanocytes
In: Cells 11 (2022), Art.Nr.: 2087
ISSN: 2073-4409
DOI: 10.3390/cells11132087
- Schott M., Kappelmann-Fenz M., Fischer S., Fernandez-Barrena MG., Pineda-Lucena A., Ávila MA., Kuphal S., Boßerhoff AK.:
Impact of CYLD on chromatin structure and histone methylation in malignant melanoma
In: International Journal of Molecular Medicine 49 (2022), Art.Nr.: 66
ISSN: 1107-3756
DOI: 10.3892/ijmm.2022.5122
- Seefried F., Haller L., Fukuda S., Thongmao A., Schneider N., Utikal J., Higashiyama S., Boßerhoff AK., Kuphal S.:
Nuclear AREG affects a low-proliferative phenotype and contributes to drug resistance of melanoma
In: International Journal of Cancer (2022)
ISSN: 0020-7136
DOI: 10.1002/ijc.34254
- Haller L., Reichelt J., Boßerhoff AK., Kuphal S.:
The Role of NRN1 in the Development and Progression of malignant Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2021
- Heppt M., Wessely A., Hornig E., Kammerbauer C., Graf S., Besch R., French LE., Kuphal S., Kappelmann-Fenzl M., Boßerhoff AK., Berking C.:
Brn3a expression is epigenetically controlled by HDAC2 in melanocytes and melanoma
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2021
- Linck-Paulus L., Lämmerhirt L., Voeller D., Meyer K., Engelmann JC., Spang R., Eichner N., Meister G., Kuphal S., Boßerhoff AK.:
Learning from Embryogenesis-A Comparative Expression Analysis in Melanoblast Differentiation and Tumorigenesis Reveals miRNAs Driving Melanoma Development
In: Journal of Clinical Medicine 10 (2021)
ISSN: 2077-0383
DOI: 10.3390/jcm10112259
- Pommer M., Kuphal S., Boßerhoff AK.:
Amphiregulin Regulates Melanocytic Senescence
In: Cells 10 (2021)
ISSN: 2073-4409
DOI: 10.3390/cells10020326
- Rachinger N., Boßerhoff AK., Kuphal S.:
Sox21-transcriptional Regulation in malignant Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2021
- Rachinger N., Fischer S., Böhme I., Linck-Paulus L., Kuphal S., Kappelmann-Fenzl M., Boßerhoff AK.:
Loss of gene information: Discrepancies between rna sequencing, cdna microarray, and qrt-pcr
In: International Journal of Molecular Sciences 22 (2021), Art.Nr.: 9349
ISSN: 1422-0067
DOI: 10.3390/ijms22179349
- Arnold J., Engelmann JC., Schneider N., Boßerhoff AK., Kuphal S.:
miR-488-5p and its role in melanoma
In: Experimental and Molecular Pathology 112 (2019)
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2019.104348
- Braun C., Schneider N., Pei D., Boßerhoff AK., Kuphal S.:
Inhibition of peptidyl-prolyl isomerase (PIN1) and BRAF signaling to target melanoma
In: American Journal of Translational Research 11 (2019), S. 4425-+
ISSN: 1943-8141
- Feuerer L., Lamm S., Henz I., Kappelmann-Fenzl M., Haferkamp S., Meierjohann S., Hellerbrand C., Kuphal S., Boßerhoff AK.:
Role of melanoma inhibitory activity in melanocyte senescence
In: Pigment Cell & Melanoma Research (2019)
ISSN: 1755-1471
DOI: 10.1111/pcmr.12801
- Kappelmann-Fenzl M., Gebhard C., Matthies AO., Kuphal S., Rehli M., Boßerhoff AK.:
C-Jun drives melanoma progression in PTEN wild type melanoma cells
In: Cell Death & Disease 10 (2019), Art.Nr.: 584
ISSN: 2041-4889
DOI: 10.1038/s41419-019-1821-9
- Kappelmann-Fenzl M., Kuphal S., Krupar R., Schadendorf D., Umansky V., Vardimon L., Hellerbrand C., Boßerhoff AK.:
Complex formation with monomeric α-tubulin and importin 13 fosters c-jun protein stability and is required for c-jun’s nuclear translocation and activity
In: Cancers 11 (2019), Art.Nr.: 1806
ISSN: 2072-6694
DOI: 10.3390/cancers11111806
- Stieglitz D., Lamm S., Braig S., Feuerer L., Kuphal S., Dietrich P., Arndt S., Echtenacher B., Hellerbrand C., Karrer S., Boßerhoff AK.:
BMP6-induced modulation of the tumor micro-milieu
In: Oncogene 38 (2019), S. 609-621
ISSN: 0950-9232
DOI: 10.1038/s41388-018-0475-x
- de Jel MM., Schott M., Lamm S., Neuhuber W., Kuphal S., Boßerhoff AK.:
Loss of CYLD accelerates melanoma development and progression in the Tg(Grm1) melanoma mouse model
In: Oncogenesis 8 (2019), Art.Nr.: 56
ISSN: 2157-9024
DOI: 10.1038/s41389-019-0169-4
- Dietrich P., Kuphal S., Spruss T., Hellerbrand C., Boßerhoff AK.:
MicroRNA-622 is a novel mediator of tumorigenicity in melanoma by targeting Kirsten rat sarcoma
In: Pigment Cell & Melanoma Research (2018)
ISSN: 1755-1471
DOI: 10.1111/pcmr.12698
- Larribere L., Kuphal S., Sachpekidis C., Hueser L., Boßerhoff AK., Utikal J.:
Targeted Therapy-Resistant Melanoma Cells Acquire Transcriptomic Similarities with Human Melanoblasts
In: Cancers 10 (2018)
ISSN: 2072-6694
DOI: 10.3390/cancers10110451
- Schott M., de Jel MM., Boßerhoff AK., Kuphal S.:
CYLD - A potential Mediator of tissue-specific Melanoma Metastasis
- Schott M., de Jel MM., Engelmann JC., Renner P., Geissler EK., Boßerhoff AK., Kuphal S.:
Selenium-binding protein 1 is down-regulated in malignant melanoma
In: Oncotarget 9 (2018), S. 10445-10456
ISSN: 1949-2553
DOI: 10.18632/oncotarget.23853
- Boßerhoff AK., Schneider N., Ellmann L., Heinzerling L., Kuphal S.:
The neurotrophin Neuritin1 (cpg15) is involved in melanoma migration, attachment independent growth, and vascular mimicry
In: Oncotarget 8 (2017), S. 1117-1131
ISSN: 1949-2553
DOI: 10.18632/oncotarget.13585
- Dietrich P., Kuphal S., Spruss T., Hellerbrand C., Boßerhoff AK.:
Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibition
In: Oncogene (2017)
ISSN: 0950-9232
DOI: 10.1038/onc.2017.391
- Kuphal S., Schneider N., Massoumi R., Hellerbrand C., Boßerhoff AK.:
UVB radiation represses CYLD expression in melanocytes
In: Oncology Letters 14 (2017), S. 7262-7268
ISSN: 1792-1074
DOI: 10.3892/ol.2017.7120